CD8 alpha anticorps

N° du produit ABIN933904

Cet anticorps Rat Monoclonal détecte spécifiquement CD8 alpha dans FACS, IHC et IP. Il présente une réactivité envers Souris.

Aperçu rapide pour CD8 alpha anticorps (ABIN933904)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 53-6-7

Détail du produit anti-CD8 alpha anticorps

Immunogène: CD8 a antibody was raised in rat using murine thymus or spleen as the immunogen.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in 100 mM BBS, pH 8.2.

Stock: 4 °C

Stockage commentaire: Store at 4 °C.

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8a

Sujet: CD8a (Cluster of Differentiation 8a), is a human gene. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified. Synonyms: Monoclonal CD8a antibody, Anti-CD8a antibody, Ly2 antibody.

Pathways: TCR Signaling